Statin Drugs

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Crestor, is a member of a class of cholesterol-lowering drugs commonly referred to as “statins”.  It was approved in the U.S. in August 2003, based on review of an extensive clinical database involving approximately 12,000 patients. At that time, the FDA identified in the WARNINGS section of the product label those patients whose increased baseline risk for myopathy warranted more careful monitoring when prescribed Crestor.

The U.S. approved labeling included a specific section titled, “Myopathy/Rhabdomyolysis”, which states that patients who are of advanced age (³ 65 years), have hypothyroidism, and/or renal insufficiency should be considered to have a greater risk for developing myopathy while receiving a statin. Physicians are warned to prescribe Crestor with caution in these patients, particularly at higher doses, as the risk of myopathy increases with higher drug levels.

Further, Astra-Zeneca Pharmaceuticals has released a revised package insert for Crestor (rosuvastatin) for use in the European Union (EU). The changes to the European labeling are in response to postmarketing spontaneous adverse event reports in patients receiving Crestor and highlight certain patient populations who may be at an increased risk for serious muscle toxicity (myopathy) associated with Crestor use, especially at the highest approved dose of 40 mg.

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       It is well established that many large corporations have profited from selling toxic products or products that cause toxic exposure without regard to the health consequences of the products.  Some of the most well known toxic products are asbestos products and bad drugs.  The asbestos products have been found to cause mesothelioma and several forms of cancer and other asbestos diseases, while dangerous drugs have been linked to death, serious heart problems, drug interactions, and suicide.  Other dangerous products that have been linked to serious disease include silica, chemical pollutants, lead, radon, EMFs, welding rods,  toxic mold infestations and other environmental toxins have caused death and serious harm to millions.  In the work environment alone undisclosed and known toxins including asbestos, silica, and welding rods have caused occupational diseases and fatalities including mesothelioma, numerous forms of cancer, and Parkinson's disease.

     This web site was created by Texas Toxic Tort Lawyer Jason Coomer and is intended only as general information on some of the most dangerous products and toxic products that have been sold by drug manufacturers, medical device manufacturers, and asbestos manufacturers, or are in use by large companies attempting to profit and make money from the sale of dangerous products that can cause serious toxic exposures.  For more information on a dangerous product or toxic exposure follow the links found above, e-mail  an inquiry to info@toxicexposurelaw.com, or submit an inquiry.

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